ABCB1 C1236T, G2677T/A and C3435T polymorphisms in systemic lupus erythematosus patients
نویسندگان
چکیده
منابع مشابه
ABCB1 C1236T, G2677T/A and C3435T polymorphisms in systemic lupus erythematosus patients.
P-glycoprotein (Pgp), the ABCB1 gene product, acts as an efflux pump that transports a large variety of substrates and is a mechanism of cell protection against xenobiotics. An increasing number of studies have shown that some ABCB1 polymorphisms may affect Pgp expression and activity, as well as affecting the development and susceptibility to diseases and pharmacological response. High activit...
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ژورنال
عنوان ژورنال: Brazilian Journal of Medical and Biological Research
سال: 2008
ISSN: 0100-879X
DOI: 10.1590/s0100-879x2008000900005